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Thinness and mortality.

S Sidney, G D Friedman, A B Siegelaub

    American Journal of Public Health
    |March 1, 1987
    PubMed
    Summary
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    Thinness is linked to higher mortality risk in current smokers, but not in never or former smokers. Long-term weight loss also showed an association with mortality in both thin and average weight individuals.

    Area of Science:

    • Epidemiology
    • Public Health
    • Biostatistics

    Background:

    • Body weight and thinness are significant factors influencing health outcomes.
    • Previous studies have yielded mixed results regarding the association between thinness and mortality.
    • Understanding these relationships is crucial for public health interventions and clinical practice.

    Purpose of the Study:

    • To investigate the relationship between thinness (low body weight) and mortality risk.
    • To compare mortality patterns between thin and average weight individuals.
    • To examine the influence of smoking status on the thinness-mortality association.

    Main Methods:

    • Analysis of data from White adult members of the Kaiser Permanente Medical Care Program.
    • Inclusion of individuals with at least three health checkups between 1964-1972 and mortality follow-up through 1980.
    Keywords:
    Age FactorsAmericasBehaviorBiologyBody WeightCaliforniaDemographic FactorsDeveloped CountriesDeveloping CountriesDifferential MortalityMortalityNorth AmericaNorthern AmericaPhysiologyPopulationPopulation DynamicsResearch ReportSex FactorsSmokingUnited States

    Related Experiment Videos

  • Comparison of mortality risks between thin (decile 1 of Quetelet's index) and average weight (deciles 4-5) cohorts, stratified by smoking status.

    • Main Results:

    • Thin male and female current smokers exhibited increased mortality risk (Relative Risk 1.6 and 2.1, respectively) compared to average weight smokers.
    • No increased mortality risk was observed for thinness in never smokers and ex-smokers (Relative Risk 1.0).
    • An association between long-term weight loss and mortality was found in both thin and average weight men, and in thin women.

    Conclusions:

    • Thinness is associated with increased mortality risk specifically in current cigarette smokers.
    • Smoking status is a critical confounder in the relationship between thinness and mortality.
    • Further research is needed to explore unmeasured factors, such as the quantity of cigarettes smoked, influencing these associations.