What happens to regulatory T cells in multiple myeloma

Huixian Chen1,2, Xueling Wang1,3, Yan Wang4

  • 1Medical Research Center, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.

Cell Death Discovery
|December 21, 2023
PubMed

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T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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