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[Risk factors and prognosis of preoperative herat failure after hip fracture]
Yan-Hui Guo1, Ye-Lai Wang1, Tian-Sheng Sun1
1Department of Orthopaedics, the 7th Medical Center, General Hospital of the Chinese People's Liberation Army, Beijing 100700, China.
Insights
Male sex, advanced age, arrhythmia, and dementia are key risk factors for heart failure in elderly patients with hip fractures. Preoperative heart failure significantly increases mortality and complication risks post-surgery.
Area of Science:
- Geriatric Medicine
- Cardiology
- Orthopedic Surgery
Context:
- Hip fractures are common in the elderly, often associated with significant comorbidities.
- Preoperative heart failure is a critical factor influencing outcomes in this population.
Purpose:
- To identify independent risk factors for preoperative heart failure in elderly hip fracture patients.
- To investigate the relationship between preoperative heart failure and prognosis, including mortality and complications.
Summary:
- A retrospective analysis of 1,569 elderly hip fracture patients identified male sex, older age, arrhythmia, and dementia as independent risk factors for preoperative heart failure.
- Patients with preoperative heart failure experienced significantly higher 30-day and 1-year mortality rates, increased incidence of pulmonary infection, cerebrovascular and cardiovascular complications, and longer hospital stays compared to those without heart failure.
Impact:
- These findings highlight the importance of screening for and managing heart failure in elderly patients undergoing hip fracture surgery.
- Identifying high-risk individuals can guide targeted interventions to improve surgical outcomes and reduce mortality.
Objective:
To explore incidence, risk factors and the relationship between preoperative heart failure and prognosis in elderly patients with hip fracture.
Methods:
A retrospective analysis was performed on 1 569 elderly patients with hip fracture treated from January 2012 to December 2019, including 522 males and 1 047 females, aged 81.00 (75.00, 90.00) years old;896 intertrochanteric fractures and 673 femoral neck fractures. Patients were divided into heart failure and non-heart failure groups according to whether they developed heart failure before surgery, and heart failure was set as the dependent variable, with independent variables including age, gender, fracture type, comorbidities and hematological indicators, etc. Univariate analysis was performed at first, and independent variables with statistical differences were included in multivariate Logistic regression analysis. Independent risk factors for preoperative heart failure were obtained. The length of hospital stay, perioperative complications, mortality at 30 days and 1 year after surgery were compared between heart failure and non-heart failure groups.
Results:
There were 91 patients in heart failure group, including 40 males and 51 females, aged 82.00 (79.00, 87.00) years old;55 patients with intertrochanteric fracture and 36 patients with femoral neck fracture. There were 1 478 patients in non-heart failure groups, including 482 males and 996 females, aged 81.00(75.00, 86.00) years old;841 patients with intertrochanteric fracture and 637 patients with femoral neck fracture. There were significant differences in age, sex, coronary heart disease, arrhythmia and dementia between two groups(P<0.05). Multivariate Logistic analysis of statistically significant factors showed that males(OR=1.609, P=0.032), age(OR=1.032, P=0.031), arrhythmia(OR=2.045, P=0.006), dementia (OR=2.106, P=0.014) were independent risk factor for preoperative heart failure. The 30-day and 1-year mortality rates were 9.9% and 26.4% in heart failure group and 3.6% and 13.8% in non-heart failure group, respectively;and had statistical significance between two groups (P<0.05). There were significant differences in pulmonary infection, cerebrovascular complications and cardiovascular complications between two groups (P<0.05). The duration of hospitalization in heart failure group was (16.21±10.64) d compared with that in non-heart failure group (13.26±8.00) d, and the difference was statistically significant (t=2.513, P=0.012).
Conclusion:
Male, old age, arrhythmia and dementia are independent risk factors for heart failure after hip fracture in elderly patients. Patients with preoperative heart failure have a higher incidence of postoperative pulmonary infection, cerebrovascular and cardiovascular complications, higher mortality at 30 d and 1 year after surgery, and longer hospital stay.
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