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Related Concept Videos

Sutures of the Skull01:22

Sutures of the Skull

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The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
6.8K

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Human otopathology in scleroderma.

Melissa Castillo-Bustamante1, Prithwijit Roychowdhury1,2, Dhrumi Gandhi1

  • 1Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear Infirmary Harvard University Boston Massachusetts USA.

Laryngoscope Investigative Otolaryngology
|December 22, 2023
PubMed
Summary

Scleroderma patients show middle and inner ear fibrosis, inflammation, and vascular changes, leading to hearing loss. This study reveals pathological ear alterations in scleroderma, impacting auditory function.

Area of Science:

  • Otopathology
  • Rheumatology
  • Immunology

Background:

  • Scleroderma is a chronic autoimmune disease causing fibrosis and vasculopathy.
Keywords:
otopathologysclerodermavasculitis

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  • Ear involvement in scleroderma is understudied, with unclear causes for hearing impairment.
  • Potential etiologies include vasculitic and autoimmune mechanisms.