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Published on: August 7, 2017
Clinical analysis of 114 cases of bronchiolitis in infants
Cheng Shi1, Meng-Hua Wu2, An Zuo1
1Department of Pediatrics, Tongling Maternal and Child Health Hospital, Tongling 244000, Anhui Province, China.
Insights
Bronchiolitis in infants primarily affects males and generally has a good prognosis. However, unnecessary antibiotic use can prolong hospital stays and burden the healthcare system.
Area of Science:
- Pediatrics
- Infectious Diseases
- Respiratory Medicine
Background:
- Bronchiolitis is a frequent lower respiratory tract infection in infants and young children.
- Severe cases can lead to significant breathing difficulties and decreased oxygen saturation.
Purpose of the Study:
- To review the clinical characteristics, diagnostic standards, and treatment protocols for bronchiolitis.
- To analyze the impact of treatment on patient outcomes and hospital resource utilization.
Main Methods:
- Retrospective analysis of 114 pediatric patients diagnosed with bronchiolitis.
- Data collected included clinical and imaging features, treatment strategies, and hospitalization duration.
- Statistical analysis of patient data to identify trends and treatment efficacy.
Main Results:
- Bronchiolitis onset predominantly occurred between 1 to 6 months of age.
- Lung imaging frequently showed increased and fuzzy lung texture (93.8%).
- Atomization therapy with Budesonide and either terbutaline or salbutamol were common treatments. Unnecessary antibiotic use in non-bacterial infections prolonged hospital stays (7.8 vs 5.7 days) and did not improve cure rates.
Conclusions:
- Infants diagnosed with bronchiolitis, particularly males, generally experience favorable outcomes.
- The study highlights that inappropriate antibiotic administration can significantly extend hospitalization, increasing patient and system costs.
- Optimizing treatment strategies, including judicious antibiotic use, is crucial for efficient pediatric respiratory care.
Background:
Bronchiolitis is a common lower respiratory tract infection in infants and young children. Severe cases may be accompanied by obvious dyspnea and oxygen saturation decline.
Aim:
To summarize the clinical features, standard diagnosis, and treatment of bronchiolitis.
Methods:
This is a retrospective analysis of 114 pediatric patients (74 males, 40 females) who were first diagnosed as having bronchioles at the Department of Pediatrics of Tongling Maternal and Child Health Hospital from January 2019 to December 2019. The clinical features, imaging features, treatment, and other clinical data were recorded and analyzed.
Results:
The age of onset of the disease was mainly from 1 mo to 6 mo (75.4%), and the time to hospital visit was mostly from the 2nd day to the 4th day of the course of the disease (75.4%). Lung imaging examination showed increase in lung texture, fuzzy (93.8%). The main treatment was atomization therapy: Budesonide combined with terbutaline (45.6%) and budesonide combined with salbutamol (38.5%). The average hospitalization time was 7.1 ± 2.4 d, and the overall cure rate was 94.7%. In patients without bacterial infection, the use of antibiotics significantly prolonged the length of hospital stay (7.8 ± 2.5 d vs 5.7 ± 1.8 d) and improved the cure rate (98.3% vs 87.9%, P < 0.05).
Conclusion:
Infants with bronchiolitis are mainly male and tend to have a good prognosis. However, the unneeded use of antibiotics may prolong the length of hospital stay significantly, which imposes the burden both on the patients and hospital system.
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