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Published on: April 6, 2012
[Retracted] MicroRNA‑29a inhibits cell migration and invasion by targeting Roundabout 1 in breast cancer cells
Hui Li1, Jiashun Luo2, Bin Xu2
1Department of Microbiology and Immunology, Medical School of Jishou University, Jishou, Hunan 416000, P.R. China.
Abstract:
Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that the Transwell migration and invasion assay data shown in Fig. 3A and B were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes that had either already been published elsewhere prior to the submission of this paper to Molecular Medicine Reports, or were under consideration for publication at around the same time (a few of which have already been retracted). In view of the fact that certain of these data had already apparently been published previously, the Editor of Molecular Medicine Reports has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [Molecular Medicine Reports 12: 3121-3126, 2015; DOI: 10.3892/mmr.2015.3749].
Insights
This study was retracted due to concerns about duplicated Transwell migration and invasion assay data. The editors decided to retract the paper after authors failed to provide an explanation.
Area of Science:
- Cellular Biology
- Biomedical Research
Context:
- Concerns were raised regarding data duplication in published research.
- Similar data appeared in multiple publications from different institutions.
Purpose:
- To address allegations of data duplication in a published study.
- To maintain the integrity of scientific publications.
Summary:
- The paper's Transwell migration and invasion assay data (Fig. 3A and B) showed striking similarities to previously published and concurrently submitted work.
- The journal editors initiated an investigation following a reader's concern about potential data overlap.
Impact:
- The paper was retracted from Molecular Medicine Reports due to unresolved data duplication concerns.
- This action underscores the importance of data integrity and originality in scientific publishing.
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