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Updated: Jun 11, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Genetics in Ischemic Stroke: Current Perspectives and Future Directions
Ka Zhang1, Shaun S E Loong2,3, Linus Z H Yuen3
1Division of Neurology, Department of Medicine, National University Hospital, Singapore 119074, Singapore.
Abstract:
Ischemic stroke is a heterogeneous condition influenced by a combination of genetic and environmental factors. Recent advancements have explored genetics in relation to various aspects of ischemic stroke, including the alteration of individual stroke occurrence risk, modulation of treatment response, and effectiveness of post-stroke functional recovery. This article aims to review the recent findings from genetic studies related to various clinical and molecular aspects of ischemic stroke. The potential clinical applications of these genetic insights in stratifying stroke risk, guiding personalized therapy, and identifying new therapeutic targets are discussed herein.
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