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Stereo-EEG-guided network modulation for psychiatric disorders: Interactive holographic planning
Angela M Noecker1, Jeffrey Mlakar2, Kelly R Bijanki3
1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
Brain Stimulation
|December 22, 2023
Summary
Holographic visualization tools like HoloSNS enhance neurosurgical planning for deep brain stimulation (DBS) by integrating complex connectomic data. This technology facilitates collaborative, interactive planning for brain network modulation therapies.
Area of Science:
- Neurosurgery
- Neuroscience
- Medical Technology
Background:
- Connectomic modeling advances understanding of brain networks targeted by deep brain stimulation (DBS).
- Integrating connectomic data into neurosurgical planning remains a challenge due to visualization difficulties.
- The 3D nature of connectomic results complicates clinical data integration.
Purpose of the Study:
- To develop and evaluate a holographic stereotactic neurosurgery research tool (HoloSNS) for interactive surgical planning.
- To enable group-based visualization and remote collaboration for neurosurgical planning.
- To integrate patient-specific brain models with connectomic hypotheses for enhanced planning.
Main Methods:
- Developed HoloSNS on the HoloLens 2 platform for group-based visualization.
- Enabled remote networking between headsets for distributed collaborative planning.
- Integrated patient-specific and atlas-based anatomical and scientific data.
Main Results:
- HoloSNS was used to plan stereo-EEG and DBS electrode placements for a clinical trial targeting depression.
- Patient models integrated extensive scientific and anatomical data, exceeding traditional workstation capabilities.
- Enabled prospective discussion and evaluation of electrode positioning based on connectomic hypotheses.
Conclusions:
- Holographic visualization is highly beneficial for neurosurgical planning.
- The 3D nature of surgical procedures, imaging, and connectomics supports holographic approaches.
- HoloSNS facilitates the design of clinical experiments exploring brain network modulation via DBS.
