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Published on: November 30, 2010
Defining treatment success in children with surgical conditions
Oliver Rivero-Arias1,2, John Buckell2, Marian Knight3
1Nuffield Department of Population Health, National Perinatal Epidemiology Unit (NPEU), University of Oxford, Oxford, UK oliver.rivero@npeu.ox.ac.uk.
Insights
A new Children's Surgery Outcome Reporting Treatment Success Score (CSOR TSS) was developed to measure successful treatment for children with surgical conditions. Quality of life and survival duration are key factors, allowing for hospital outcome comparisons.
Area of Science:
- Pediatric Surgery
- Health Outcomes Research
- Patient-Reported Outcomes
Background:
- Assessing treatment success in pediatric surgery is complex.
- Existing metrics may not fully capture patient and family priorities.
- A standardized score is needed to evaluate surgical outcomes in children.
Purpose of the Study:
- To develop a novel score for summarizing treatment success in children with any surgical condition.
- To rigorously test the clinical validity of this new score.
Main Methods:
- A discrete choice experiment (DCE) involving patients, caregivers, healthcare professionals, and the general population.
- Secondary analysis of data from six UK-wide prospective cohort studies.
- Utilized Normalized Importance Value of Attribute (NIVA) to weigh key outcome attributes.
Main Results:
- Quality of life and duration of survival were identified as the most critical factors for treatment success.
- Parents/carers and adults prioritized both equally, while healthcare professionals favored quality of life and the general population favored survival.
- The developed Children's Surgery Outcome Reporting Treatment Success Score (CSOR TSS) demonstrated appropriate clinical variation in a cohort of infants.
Conclusions:
- The CSOR TSS effectively summarizes treatment success for pediatric surgical patients.
- This score can be utilized to compare observed versus expected outcomes across different hospitals.
- The CSOR TSS provides a valuable tool for quality improvement in pediatric surgical care.
Objectives:
Develop a score summarising how successfully a child with any surgical condition has been treated, and test the clinical validity of the score.
Design:
Discrete choice experiment (DCE), and secondary analysis of data from six UK-wide prospective cohort studies.
Participants:
253 people with lived experience of childhood surgical conditions, 114 health professionals caring for children with surgical conditions and 753 members of the general population completed the DCE. Data from 1383 children with surgical conditions were used in the secondary analysis.
Main Outcome Measures:
Normalised importance value of attribute (NIVA) for number/type of operations, hospital-treated infections, quality of life and duration of survival (reference attribute).
Results:
Quality of life and duration of survival were the most important attributes in deciding whether a child had been successfully treated. Parents, carers and previously treated adults placed equal weight on both attributes (NIVA=0.996; 0.798 to 1.194). Healthcare professionals placed more weight on quality of life (NIVA=1.469; 0.950 to 1.987). The general population placed more weight on survival (NIVA=0.823; 95% CI 0.708 to 0.938). The resulting score (the Children's Surgery Outcome Reporting (CSOR) Treatment Success Score (TSS)) has the best possible value of 1, a value of 0 describes palliation and values less than 0 describe outcomes worse than palliation. CSOR TSSs varied clinically appropriately for infants whose data were included in the UK-wide cohort studies.
Conclusions:
The CSOR TSS summarises how successfully children with surgical conditions have been treated, and can therefore be used to compare hospitals' observed and expected outcomes.
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