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NADES-Assisted Extraction of Polyphenols from Coriander Seeds: A Systematic Optimization Study
Federica Ianni1, Samir Scandar2, Luciano Mangiapelo1
1Department of Pharmaceutical Sciences, Section of Food, Biochemical, Physiological and Nutrition Sciences, University of Perugia, 06126 Perugia, Italy.
Antioxidants (Basel, Switzerland)
|December 23, 2023
Summary
This study explored natural deep eutectic solvents (NADES) for extracting polyphenols from coriander seeds. Optimized NADES and extraction methods, like ultrasound-assisted extraction (UAE), efficiently recovered specific phenolic acids and rutin.
Area of Science:
- Agricultural and Food Chemistry
- Natural Product Chemistry
- Green Chemistry
Background:
- Coriandrum sativum L. seeds are traditionally used in medicine, with known nutritional components like linalool and petroselinic acid.
- The polyphenolic fraction of coriander seeds remains underexplored, necessitating advanced extraction techniques.
- Natural Deep Eutectic Solvents (NADES) offer a sustainable approach for extracting bioactive compounds from plant materials.
Purpose of the Study:
- To develop a one-step methodology for recovering polyphenols from coriander seeds using NADES.
- To evaluate the efficacy of different NADES (choline chloride-based) combined with maceration (MAC) and ultrasound-assisted extraction (UAE).
- To systematically optimize polyphenol extraction by modulating NADES composition and extraction techniques.
Main Methods:
- Green extraction using various NADES, including choline chloride-citric acid (ChCl:CA), choline chloride-urea (ChCl:Ur), and choline chloride-glucose (ChCl:Glu).
- Comparison of conventional maceration (MAC) and non-conventional ultrasound-assisted extraction (UAE) techniques.
- Quantitative analysis of extracted polyphenols, including chlorogenic acid, its isomer, protocatechuic acid, caffeic acid, p-coumaric acid, and rutin.
Main Results:
- ChCl:Ur combined with UAE significantly enhanced the extraction of chlorogenic acid and its isomer.
- ChCl:Glu with UAE improved the recovery of protocatechuic, caffeic, and p-coumaric acids.
- The highest rutin yield was achieved using ChCl:CA-based NADES with the MAC technique.
Conclusions:
- NADES composition can be tailored to selectively enhance the extraction of specific polyphenols from coriander seeds.
- The combination of NADES with UAE or MAC provides an efficient, one-step method for recovering valuable bioactive compounds.
- This approach holds potential for the targeted isolation of desirable phenolics for various applications.
