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Neonatal typhoid fever.

K C Chin, E J Simmonds, M J Tarlow

    Archives of Disease in Childhood
    |December 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Neonatal typhoid fever, caused by Salmonella typhi, affected three infants born to Pakistani immigrant mothers. While all infants survived, two became chronic carriers, highlighting outbreak risks in maternity settings.

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    Area of Science:

    • Infectious Diseases
    • Public Health
    • Neonatal Medicine

    Background:

    • Typhoid fever poses a significant global health challenge, particularly in regions with limited sanitation.
    • Neonatal infections can have severe consequences, necessitating prompt diagnosis and management.

    Observation:

    • Three infants born to Pakistani immigrant mothers presented with typhoid fever during the neonatal period.
    • Clinical presentation and outcomes varied among the affected infants.

    Findings:

    • All three infants survived the initial typhoid fever infection.
    • Two of the three infants developed into chronic excretors of Salmonella typhi.
    • Chronic Salmonella typhi excretion poses a risk of ongoing transmission.

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    Implications:

    • The findings underscore the importance of considering typhoid fever in the differential diagnosis of febrile illnesses in neonates, especially in immigrant populations.
    • Healthcare providers in maternity and special care baby units must be vigilant for potential outbreaks of typhoid fever.
    • Public health strategies should address the prevention and control of typhoid fever transmission in vulnerable neonatal populations.