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Induction of Programmed Cell Death in Acanthamoeba culbertsoni by the Repurposed Compound Nitroxoline

Rubén L Rodríguez-Expósito1,2, Ines Sifaoui1,2, María Reyes-Batlle1,2

  • 1Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna (ULL), Avda. Astrofísico Fco. Sánchez, S/N, 38203 San Cristóbal de La Laguna, Spain.

Antioxidants (Basel, Switzerland)
|December 23, 2023
PubMed
Summary

Nitroxoline demonstrates potent amoebicidal activity against Acanthamoeba, effectively targeting both trophozoite and cyst stages. This study highlights nitroxoline

Keywords:
Acanthamoebaautophagycytoskeletonnitroxolineprogrammed cell deathproteomic analysis

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