SOX2-OT Binds with ILF3 to Promote Head and Neck Cancer Progression by Modulating Crosstalk between STAT3 and TGF-β

Ru Wang1,2, Yifan Yang1,2, Lingwa Wang1,2

  • 1Department of Otorhinolaryngology, Head and Neck Surgery, Beijing Tong Ren Hospital, Capital Medical University, 1 Dongjiaominxiang Street, Beijing 100730, China.

Cancers
|December 23, 2023
PubMed
Summary

Long non-coding RNA SOX2-OT promotes head and neck squamous cell carcinoma (HNSCC) progression and metastasis. Overexpression of SOX2-OT indicates a poor prognosis for HNSCC patients, suggesting it as a potential therapeutic target.

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