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Reduced Age-Related Gray Matter Loss in the Orbitofrontal Cortex in Long-Term Meditators
Florian Kurth1, Sarah Strohmaier2, Eileen Luders1,3,4
1School of Psychology, University of Auckland, Auckland 1010, New Zealand.
Brain Sciences
|December 23, 2023
Summary
Long-term meditation may preserve orbitofrontal cortex (OFC) gray matter volume in aging. Meditation practitioners showed a less steep age-related decline in OFC subregions compared to controls.
Area of Science:
- Neuroscience
- Cognitive Psychology
- Aging Research
Background:
- The orbitofrontal cortex (OFC) is crucial for cognitive functions influenced by meditation.
- OFC volume decreases with age and differs between meditators and non-meditators.
Purpose of the Study:
- To investigate if meditation mitigates the age-related decline in OFC gray matter volume.
- To compare age-related OFC volume changes in long-term meditators versus matched controls.
Main Methods:
- Correlated chronological age with regional gray matter volumes of the OFC and its subregions (Fo1-Fo7).
- Studied 50 long-term meditators and 50 matched non-meditator controls.
Main Results:
- Both groups showed age-related decreases in OFC volume.
- The age-related decline was significantly less pronounced in meditators compared to controls.
- Specific OFC subregions (Fo2, Fo3, Fo4, Fo7, left Fo5, right Fo6) showed significant differences.
Conclusions:
- Long-term meditation practice may attenuate the age-related gray matter volume loss in specific OFC subregions.
- These findings suggest a potential neuroprotective effect of meditation on the aging brain.
- Further research is needed to understand the functional implications of these structural changes.
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