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Related Concept Videos

Biofilms01:29

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
Bioreactor Design and Operational System01:29

Bioreactor Design and Operational System

Bioreactors are engineered vessels designed to cultivate microorganisms under controlled conditions for industrial bioprocessing. They maintain sterility and allow precise regulation of pH, temperature, oxygen, and nutrient levels to optimize microbial growth and metabolite production. Bioreactors range from small laboratory units of 1 liter to industrial systems holding up to 500,000 liters, though only about 75% of their volume is actively used for fermentation. The remaining headspace...
Bioreactor Controls-II01:18

Bioreactor Controls-II

In aerobic fermentations, oxygen is vital for microbial growth and metabolite production. Since air comprises only about 20% oxygen and the gas is poorly soluble in water—just 9 ppm at 20°C—supplying sufficient oxygen becomes a critical challenge, especially in high-demand processes like yeast growth or citric acid production. Even a fully saturated broth may offer only a few seconds of oxygen availability.To address this, sterile or scrubbed air is introduced into the fermentor via a sparger...

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Use of a High-throughput In Vitro Microfluidic System to Develop Oral Multi-species Biofilms
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Multispecies Bacterial Biofilms and Their Evaluation Using Bioreactors.

Grishma S Prabhukhot1, Charles D Eggleton1, Jitendra Patel2

  • 1Department of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA.

Foods (Basel, Switzerland)
|December 23, 2023
PubMed
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Preventing pathogenic bacterial biofilms in food processing is vital for public health and the economy. Tailored strategies are crucial, as biofilm behavior varies with environmental conditions.

Keywords:
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Area of Science:

  • Food safety
  • Microbiology
  • Biotechnology

Background:

  • Pathogenic biofilms in food processing pose significant public health and economic risks.
  • Biofilm formation is a complex, multi-step process on equipment surfaces.
  • Understanding biofilm dynamics is critical for effective control in food industries.

Purpose of the Study:

  • To review the stages of bacterial biofilm formation.
  • To discuss the influence of surface properties and shear stress on biofilms.
  • To explore bioreactor types and antimicrobial coatings for biofilm management.

Main Methods:

  • Literature review on biofilm formation stages.
  • Analysis of factors affecting biofilm development (surface properties, shear stress).
  • Examination of bioreactor applications and antimicrobial coating efficacy.

Main Results:

  • Biofilm prevention is the primary defense, followed by control measures.
  • Eradication strategies must be specific due to variable biofilm behavior.
  • Bioreactors are essential for studying biofilm mechanisms.

Conclusions:

  • Prioritizing prevention and employing targeted control are key to managing food industry biofilms.
  • Antimicrobial coatings offer promise in minimizing bacterial attachment.
  • Further research using appropriate bioreactors is needed for effective biofilm investigation.