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Related Experiment Video

Updated: Jul 7, 2025

An Experimental Paradigm for Measuring the Effects of Ageing on Sentence Processing
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Syntactic Errors in Older Adults with Depression.

Chengjie Xu1, Nahathai Wongpakaran1,2, Tinakon Wongpakaran1,2

  • 1Master of Science Program in Mental Health, Multidisciplinary and Interdisciplinary School, Chiang Mai University, Chiang Mai 50200, Thailand.

Medicina (Kaunas, Lithuania)
|December 23, 2023
PubMed
Summary
This summary is machine-generated.

Major depressive disorder in older adults is linked to poorer syntactic abilities and cognitive function. Higher depression severity correlated with lower syntax scores, suggesting a connection between mood and language skills.

Keywords:
cognitivelate-life depressionlinguisticmajor depressive disorderolder populationsyntax

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Area of Science:

  • Neuroscience
  • Psycholinguistics
  • Gerontology

Background:

  • Major depressive disorder (MDD) is prevalent in older adults.
  • Cognitive function and language abilities can be affected by aging and depression.
  • Syntactic processing is a complex cognitive function potentially vulnerable to depressive symptoms.

Purpose of the Study:

  • To compare syntactic error rates between older adults with and without major depressive disorder.
  • To assess cognitive function differences across groups.
  • To examine the relationship between depression severity and syntactic performance.

Main Methods:

  • Forty-four older adults participated, assessed using the Mini-Cog for dementia screening.
  • The 15-item Geriatric Depression Scale (TGDS-15) and specific language tests were administered.
  • Clinical psychologists evaluated language tests and syntax scores following a single-anonymized procedure.

Main Results:

  • Participants with major depressive disorder exhibited lower syntax scores compared to non-depressed individuals.
  • Cognitive test performance was generally lower in the depressed group.
  • A significant negative correlation was found between depression severity and syntax scores (r = -0.426).

Conclusions:

  • Major depressive disorder is associated with diminished syntactic abilities in older adults.
  • The findings suggest a link between depression severity and language processing deficits.
  • Limitations include a modest sample size; cultural and linguistic factors were considered potential confounders.