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Selenium Nanoparticles: Green Synthesis and Biomedical Application.

Ekaterina O Mikhailova1

  • 1Institute of Innovation Management, Kazan National Research Technological University, K. Marx Street 68, 420015 Kazan, Russia.

Molecules (Basel, Switzerland)
|December 23, 2023
PubMed
Summary

Green synthesis of selenium nanoparticles (SeNPs) using biological sources like plants and microbes offers eco-friendly, cost-effective nanomaterial production. These SeNPs show promising biomedical applications due to their diverse therapeutic properties.

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Area of Science:

  • Nanotechnology
  • Biotechnology
  • Materials Science

Background:

  • Selenium nanoparticles (SeNPs) are gaining prominence in nanotechnology.
  • There is a growing demand for environmentally friendly, non-toxic, and low-cost synthesis methods.
  • Green synthesis offers a sustainable approach to producing SeNPs.

Purpose of the Study:

  • To review the biosynthesis mechanisms of SeNPs using various biological entities.
  • To explore the role of biomolecules in SeNP formation and stabilization.
  • To present current information on the biomedical applications and therapeutic potential of SeNPs.

Main Methods:

  • Review of biosynthesis pathways involving bacteria, fungi, algae, and plants.
  • Analysis of the reduction and stabilization mechanisms of selenium compounds into SeNPs.
Keywords:
antibacterial activityanticancer activitycapping agentsgreen synthesisselenium nanoparticles

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  • Compilation of data on the biomedical properties and underlying mechanisms of SeNPs.

    • Main Results:

    • Biological synthesis effectively produces SeNPs using diverse natural sources.
    • Various biomolecules facilitate the reduction of selenium and the formation of stable SeNPs.
    • SeNPs exhibit significant antimicrobial, antiviral, anticancer, antioxidant, and anti-inflammatory activities.

    Conclusions:

    • Green synthesis is a viable and sustainable method for producing SeNPs.
    • SeNPs possess multifaceted biomedical properties with significant therapeutic potential.
    • Further research into SeNP mechanisms can unlock advanced therapeutic strategies.