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Related Concept Videos

Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

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Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
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The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
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Liver Histology01:27

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The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
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Gross Anatomy of the Liver01:17

Gross Anatomy of the Liver

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The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is...
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Liver Physiology01:30

Liver Physiology

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The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of  70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
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Related Experiment Video

Updated: Jul 7, 2025

Establishment of Hepatocarcinoma in BALB/c-nu Mice and Investigation of the Therapeutic Effect of the Sanleng Jiashen Formula
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Published on: January 26, 2024

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Liver Cancer 2.0.

Hiroaki Taniguchi1

  • 1Department of Experimental Embryology, Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, 05-552 Jastrzebiec, Poland.

International Journal of Molecular Sciences
|December 23, 2023
PubMed
Summary
This summary is machine-generated.

Hepatocellular carcinoma (HCC) is a prevalent liver cancer globally. Research is crucial for understanding and combating this major health concern.

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Area of Science:

  • Hepatology and Oncology
  • Global Health Research

Background:

  • Hepatocellular carcinoma (HCC) represents a significant global health challenge.
  • High prevalence rates necessitate urgent research into liver cancer.
  • Understanding HCC epidemiology is critical for public health strategies.

Discussion:

  • The study addresses the critical need for advanced research in liver cancer.
  • Focuses on hepatocellular carcinoma (HCC) as a primary liver malignancy.
  • Highlights the global burden and impact of liver cancer.

Key Insights:

  • HCC is a leading cause of cancer-related mortality worldwide.
  • Geographical variations in HCC prevalence underscore the need for targeted interventions.
  • Early detection and treatment strategies remain paramount.

Outlook:

  • Future research should explore novel therapeutic targets for HCC.
  • Continued investigation into risk factors and prevention is essential.
  • International collaboration can accelerate progress in combating liver cancer.