Attitudes towards Receiving Monkeypox Vaccination: A Systematic Review and Meta-Analysis

Area of Science:

• Public Health
• Epidemiology
• Vaccinology

Background:

• Public attitudes towards Mpox vaccination are crucial for immunization program success.
• Understanding vaccine acceptance and hesitancy is key for effective health communication.
• This review synthesizes evidence on public attitudes toward Mpox vaccination.

Purpose of the Study:

• To systematically review and meta-analyze observational studies on public attitudes toward Mpox vaccination.
• To identify factors influencing willingness and rejection of the Mpox vaccine.
• To inform public health strategies for Mpox immunization.

Main Methods:

• A comprehensive literature search was conducted across PubMed, Web of Science, Scopus, and EBSCO databases until June 2023.
• Inclusion criteria focused on studies examining public attitudes (acceptance vs. rejection) towards Mpox vaccination.
• Systematic review and meta-analysis of eligible observational studies.

Main Results:

• Thirty studies involving over 89,000 participants were included.
• 56.14% of participants were willing to receive the Mpox vaccine, while 28.94% were unwilling.
• Females showed lower willingness (OR 0.61) compared to males; homosexual individuals showed higher willingness (OR 1.44) than heterosexual individuals.

Conclusions:

• Mpox vaccination is vital for preventing infection and achieving herd immunity.
• Enhancing public awareness and acceptance of vaccination is critical to prevent widespread outbreaks.
• Targeted educational programs can bridge information gaps and promote proactive public health measures against emerging infectious diseases.