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[Adherence to pharmacological treatments: searching for new solutions]

Stefania Angela Di Fusco1, Antonella Spinelli1, Giuseppe Di Pasquale2

  • 1U.O.C. Cardiologia Clinica e Riabilitativa, Dipartimento Emergenza e Accettazione, Presidio Ospedaliero San Filippo Neri - ASL Roma 1, Roma.

Giornale Italiano Di Cardiologia (2006)
|December 23, 2023
PubMed

Insights

Poor adherence to cardiovascular treatments impacts patient outcomes and healthcare costs. This review explores causes and interventions like deprescribing, polypills, gene silencing, and digital health to improve patient adherence.

Area of Science:

  • Cardiology
  • Pharmacology
  • Digital Health

Background:

  • Poor therapeutic adherence affects 50% of primary prevention and 44% of secondary prevention cardiology patients.
  • Non-adherence significantly impacts patient prognosis and incurs substantial global health costs.

Approach:

  • This review analyzes the multifaceted causes of poor therapeutic adherence in cardiovascular care.
  • It discusses various interventions aimed at improving patient compliance with prescribed treatments.

Key Points:

  • Deprescribing strategies can simplify medication regimens.
  • The use of a polypill offers a consolidated approach to managing multiple cardiovascular risk factors.
  • Innovative treatments, including gene silencing, represent novel therapeutic avenues.
  • Digital technologies provide tools for monitoring and enhancing patient adherence.

Conclusions:

  • Addressing poor adherence is crucial for effective cardiovascular therapy.
  • A combination of pharmacological adjustments, novel treatments, and digital solutions holds promise for improving patient adherence and outcomes.

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