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Updated: Jul 31, 2026

Hydrophobic Salt-modified Nafion for Enzyme Immobilization and Stabilization
Published on: July 11, 2012
On the NADPH dependent reaction of cytoplasmic sn-glycerol-3-phosphate dehydrogenase
Abstract:
Cytoplasmic sn-glycerol-3-phosphate dehydrogenase (EC. 1.1.1.8.) can reduce dihydroxy acetone phosphate with NADPH as coenzyme under in vitro conditions, in solutions of low ionic strengths, at pH values lower than 7. The reaction is inhibited by phosphoenolpyruvate, NAD, ATP, ADP and Pi. In the cell this reaction can occur apparently only in case of specific metabolic conditions, i.e. when the local pH is low and the enzyme is protected from the inhibition by the above listed metabolites.
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