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Platelet-rich plasma for pilonidal disease: a systematic review
1Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
The Journal of International Medical Research
|December 23, 2023
Summary
Platelet-rich plasma (PRP) effectively treats pilonidal disease (PD) by reducing pain and improving healing. This adjuvant therapy enhances surgical outcomes and minimizes adverse events in PD patients.
Area of Science:
- Regenerative Medicine
- Surgical Innovation
Background:
- Pilonidal disease (PD) presents a significant clinical challenge, necessitating effective treatment strategies.
- Platelet-rich plasma (PRP) has emerged as a promising therapeutic agent in various medical fields.
Approach:
- A systematic review was conducted on PubMed and Cochrane Library databases.
- Included eight randomized controlled trials and one prospective cohort study with 809 patients.
- Data extraction focused on PRP application, surgical techniques, outcomes, and adverse events.
Key Points:
- PRP application in PD treatment demonstrated reduced pain and accelerated wound healing.
- Combined minimally invasive surgery with PRP yielded superior therapeutic results.
- Potential for increased adverse events was noted with excessive PRP application in minimally invasive procedures.
Conclusions:
- PRP serves as a beneficial adjuvant therapy in pilonidal disease surgery.
- It improves therapeutic efficacy and reduces the incidence of adverse events.
- Further research is needed to optimize PRP combination protocols for PD management.
