Impact of Weight on Severity of Hospital Course in Children Admitted With COVID-19

Nessa Tantivit1, Madhuri Mulekar1, Anne-Marie Kaulfers1

  • 1University of South Alabama, Mobile, AL, USA.

Global Pediatric Health
|December 25, 2023
PubMed

Insights

Weight status impacts COVID-19 outcomes in children. Higher BMI percentile in older children and lower weight-for-age percentile in younger children correlate with increased oxygen needs and longer hospital stays.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Background:

  • COVID-19 affects children, with varying severity.
  • Understanding factors influencing pediatric COVID-19 outcomes is crucial for effective management.

Purpose of the Study:

  • To investigate the relationship between weight status and clinical outcomes in hospitalized children with COVID-19.
  • To determine if weight parameters like Body Mass Index (BMI) percentile and weight-for-age (WFA) percentile influence length of stay (LOS) and oxygen requirements.

Main Methods:

  • Retrospective review of 153 pediatric COVID-19 admissions (March 2020 - October 2021).
  • Weight status assessed using BMI percentile for children ≥2 years and WFA percentile for children <2 years.
  • Analysis of correlations between weight status, LOS, and oxygen need.

Main Results:

  • Distinct patterns observed for children <2 years and ≥2 years.
  • Children ≥2 years with BMI ≥85th percentile had higher likelihood of oxygen requirement and LOS ≥5 days (P=.0415, P=.0197).
  • In children <2 years, decreasing WFA percentile correlated with increased oxygen need (P=.0325) and negatively with LOS (r=-.31, P=.0123).

Conclusions:

  • Age-specific stratification of pediatric COVID-19 patients based on weight status is essential.
  • BMI and WFA percentiles are important indicators for predicting severity and resource utilization in hospitalized children with COVID-19.

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