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Long-Acting Cabotegravir/Rilpivirine Concentrations in Combination With Intravenous Rifampin: A Case Report
Shawnalyn W Sunagawa1, Joshua P Havens1,2, Anthony Podany1
1College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Abstract:
As antiretroviral therapy advancements focus on long-acting medications, there is a need to assess the potential impact of drug-drug interactions. We present a real-world case of long-acting cabotegravir/rilpivirine co-administered with intravenous rifampin. The combination resulted in both cabotegravir and rilpivirine concentrations falling below 4 times the protein-adjusted IC90.
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