Clinical characteristics and mortality in all Czech patients after pacemaker implantation in the last decade

Area of Science:

• Cardiology
• Public Health
• Medical Device Registries

Background:

• Analysis of mortality data from national health registries and the REPACE registry for Czech pacemaker patients.
• Examining trends and outcomes associated with pacemaker implantation in a national cohort.

Purpose of the Study:

• To analyze mortality patterns in Czech patients who received pacemakers between 2010 and 2021.
• To compare pacemaker implantation data between the REPACE registry and national health records.

Main Methods:

• Retrospective observational analysis of 82,791 Czech patients undergoing pacemaker implantation from 2010-2021.
• Utilized data from the REPACE registry and the National Register of Reimbursed Health Services for validation.
• Categorized pacemakers into single-chamber, dual-chamber, and biventricular devices.

Main Results:

• Nearly 114,000 pacemakers were implanted, with a steady annual increase except for a dip in 2020 (likely COVID-19 related).
• Observed 5-year relative survival was 88.6% and 10-year relative survival was 75.9%.
• Causes of death varied by patient age; pacemaker recipients showed significantly higher mortality than the general population.

Conclusions:

• Pacemaker implantations in the Czech Republic show a consistent upward trend.
• Patients with pacemakers exhibit increased mortality risk compared to the general population.
• The REPACE registry data demonstrates high concordance with national health service records.