Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

North American Society for Interventional Thyroidology (NASIT) Statement on Directed Ablative Therapy for the Management of of Low Risk Papillary Thyroid Carcinoma.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same author

Temperature-Driven Switching Between Block, Near-Statistical, and Gradient Copolymers Enabled by Multinuclear Aluminum Catalysis.

Macromolecular rapid communications·2026
Same author

The American Thyroid Association Multidisciplinary Consensus Statement on Ambulatory Thyroid Surgery.

Thyroid : official journal of the American Thyroid Association·2026
Same author

Evaluating the Efficacy of a Novel Multimaterial 3D-Printed Phantom for Otologic Surgical Education and Simulation.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·2026
Same author

Xanthene-anchored salen-based open and closed dinuclear indium complexes: synthesis and photophysical properties.

Dalton transactions (Cambridge, England : 2003)·2026
Same author

Evaluating Artificial Intelligence Chatbots for Patient Education on Thyroid Radiofrequency Ablation: An Analysis of Accuracy, Quality, and Readability.

Thyroid : official journal of the American Thyroid Association·2026
Same journal

Vocal Cord Monitoring by Flexible Fiberoptic Laryngoscopy During Thyroid Radiofrequency Ablation.

VideoEndocrinology·2023
Same journal

Precision Medicine with 3D Ultrasound.

VideoEndocrinology·2023
Same journal

Stretching Exercise for the Prevention of Postoperative Neck Symptoms Following Thyroid Surgery.

VideoEndocrinology·2022
Same journal

Parathyroid Function Saving Total Thyroidectomy Using Autofluorescence and Quantified Indocyanine Green Angiography.

VideoEndocrinology·2021
Same journal

Intraoperative Mapping Angiography of the Parathyroid Glands: Description, Advantages, and Limits of the Technique.

VideoEndocrinology·2021
Same journal

Lateral Neck Dissection for Papillary Thyroid Cancer.

VideoEndocrinology·2021
See all related articles

Related Experiment Video

Updated: Jul 7, 2025

Tissue-simulating Phantoms for Assessing Potential Near-infrared Fluorescence Imaging Applications in Breast Cancer Surgery
11:05

Tissue-simulating Phantoms for Assessing Potential Near-infrared Fluorescence Imaging Applications in Breast Cancer Surgery

Published on: September 19, 2014

12.2K

Handheld Autofluorescence Imaging System for Intraoperative Parathyroid Detection.

Nimesh V Nagururu1, Khalid Mohamed Ali1, Stefanie Seo1

  • 1Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

Videoendocrinology
|December 25, 2023
PubMed
Summary
This summary is machine-generated.

A new near-infrared autofluorescence (NIRAF) device, hANDY-i, aids surgeons in identifying parathyroid glands during thyroid surgery. This technology improves visualization and accessibility, reducing complications like hypoparathyroidism.

Keywords:
NIRAFautofluorescenceparathyroid

More Related Videos

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
06:37

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

23.3K
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

3.5K

Related Experiment Videos

Last Updated: Jul 7, 2025

Tissue-simulating Phantoms for Assessing Potential Near-infrared Fluorescence Imaging Applications in Breast Cancer Surgery
11:05

Tissue-simulating Phantoms for Assessing Potential Near-infrared Fluorescence Imaging Applications in Breast Cancer Surgery

Published on: September 19, 2014

12.2K
Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
06:37

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

23.3K
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

3.5K

Area of Science:

  • Surgical Technology
  • Medical Imaging
  • Endocrinology

Background:

  • Hypoparathyroidism and hypocalcemia are common post-thyroidectomy complications.
  • Parathyroid glands are challenging to identify during surgery, leading to accidental damage or removal.
  • Intraoperative optical technologies, like near-infrared autofluorescence (NIRAF), are emerging to aid parathyroid identification.

Purpose of the Study:

  • To introduce the hANDY-i, a developing NIRAF device for parathyroid visualization.
  • To compare the hANDY-i device with existing FDA-approved technologies.
  • To demonstrate the preliminary intraoperative performance of the hANDY-i device.

Main Methods:

  • The hANDY-i device utilizes a 785nm laser excitation module.
  • It integrates co-registered red-green-blue (RGB) and near-infrared cameras.
  • Preliminary intraoperative use was documented to assess device operation and output.

Main Results:

  • The hANDY-i produced clear, side-by-side NIRAF and RGB images.
  • It demonstrated high contrast between parathyroid glands and surrounding tissues.
  • The device proved effective in both in vivo and ex vivo settings and is compatible with operating room lighting.

Conclusions:

  • The hANDY-i prototype advances NIRAF technology by reducing light sensitivity and improving image output.
  • This innovation makes NIRAF more accessible and less disruptive to surgical workflows.
  • The device shows promise in enhancing surgical precision and patient outcomes by better identifying parathyroid glands.