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Updated: Jul 7, 2025
Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
Published on: July 4, 2007
Case report: atypical presentation of acute disseminated encephalomyelitis after tick-borne encephalitis
Adam Garkowski1, Jakub Okrzeja2, Bożena Kubas1
1Department of Radiology, Medical University of Białystok, Białystok, Poland.
Abstract:
Acute disseminated encephalomyelitis (ADEM) is a rare and an immune- mediated inflammatory illness of the central nervous system that normally demonstrates as a monophasic disorder connected with multifocal neurologic symptoms. Herein, we report atypical presentation of ADEM presenting as single lesions in a middle-aged woman after tick-borne encephalitis.
Insights
Acute disseminated encephalomyelitis (ADEM) is a rare immune-mediated CNS disorder. This case report details an unusual ADEM presentation with a single lesion following tick-borne encephalitis in a middle-aged woman.
Area of Science:
- Neuroimmunology
- Infectious Neurology
- Demyelinating Diseases
Background:
- Acute disseminated encephalomyelitis (ADEM) is typically a monophasic, immune-mediated inflammatory condition of the central nervous system.
- ADEM commonly presents with multifocal neurological deficits.
Observation:
- This report describes an atypical case of ADEM in a middle-aged woman.
- The patient developed symptoms following tick-borne encephalitis.
Findings:
- The patient exhibited a single lesion on neuroimaging, deviating from the typical multifocal presentation of ADEM.
- This suggests a potential link between tick-borne encephalitis and atypical ADEM manifestation.
Implications:
- This case highlights the importance of considering ADEM in patients with neurological symptoms post-tick-borne encephalitis, even with atypical lesion patterns.
- Understanding rare presentations of ADEM is crucial for accurate diagnosis and management of central nervous system inflammatory disorders.
