Related Experiment Video

Updated: Jul 7, 2025

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

8.2K

Food-induced anaphylaxis during infancy is associated with later sleeping and eating disorders

Shay Nemet1, Daniel Elbirt1, Keren Mahlab-Guri1

  • 1Allergy and Clinical Immunology Unit, Kaplan Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Rehovot, Jerusalem, Israel.

Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
|December 26, 2023
PubMed

Insights

Food-induced anaphylaxis (FIA) in early childhood significantly raises the risk of developing psychological disorders, particularly eating and sleeping disorders. These conditions may persist into adulthood, requiring early diagnosis and intervention.

Area of Science:

  • Pediatric Allergy and Immunology
  • Developmental Psychology
  • Public Health

Background:

  • Food-induced anaphylaxis (FIA) is increasingly linked to psychological disorders (PDs).
  • Early-life FIA may have a specific impact on subsequent PD development.
  • This study investigates the long-term psychological effects of early-onset FIA.

Purpose of the Study:

  • To evaluate the association between early-life food-induced anaphylaxis and the development of psychological disorders.
  • To identify specific types of psychological disorders linked to FIA in pediatric patients.
  • To assess the long-term risk of PDs following FIA in early childhood.

Main Methods:

  • Population-based, retrospective, matched-cohort study.
  • Inclusion of pediatric patients (≤18 years) from 2001-2021.
  • Propensity score matching of FIA patients with controls without allergies.
  • Multivariable regression models and Kaplan-Meier analysis to examine associations.

Main Results:

  • An association was found between FIA and any PDs (p<.001), sleeping disorders (p<.001), and eating disorders (p=.050).
  • Patients experiencing FIA before age 3 had an increased cumulative risk of developing PDs, including eating and sleeping disorders.
  • Major allergens in young children included cow's milk, eggs, and peanuts.

Conclusions:

  • Early-life FIA (before age 3) is a risk factor for developing eating and sleeping disorders later in life.
  • These disorders can manifest and persist into adulthood.
  • Increased clinical attention is needed for accurate diagnosis of psychological disorders in children with FIA.
Abstract

Keywords:
anaphylaxiseating disordersfood allergyfood-induced anaphylaxispsychological disorderssleep disorders

More Related Videos

A Treatment Package without Escape Extinction to Address Food Selectivity04:23

A Treatment Package without Escape Extinction to Address Food Selectivity

Published on: August 21, 2015

11.6K
Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

25.6K

Related Concept Videos

Conditioned Taste Aversion01:14

Conditioned Taste Aversion

Conditioned taste aversion, also known as sauce béarnaise syndrome, is a phenomenon in which an individual develops an aversion to a certain food taste following a negative experience, typically illness. This form of aversion is a type of classical conditioning in which the taste of the food (conditioned stimulus, CS) is associated with the experience of illness (unconditioned stimulus, UCS).
A notable characteristic of conditioned taste aversion is that it often requires only a single...
146
Allergic Reactions02:06

Allergic Reactions

Overview
27.4K
Cause and Effect01:53

Cause and Effect

While variables are sometimes correlated because one does cause the other, it could also be that some other factor, a confounding variable, is actually causing the systematic movement in our variables of interest. For instance, as sales in ice cream increase, so does the overall rate of crime. Is it possible that indulging in your favorite flavor of ice cream could send you on a crime spree? Or, after committing crime do you think you might decide to treat yourself to a cone?
10.9K
Binge Eating Disorders01:23

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
70
Anorexia Nervosa01:28

Anorexia Nervosa

Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
73
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
672