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Updated: Jul 7, 2025

Author Spotlight: Investigating the Underlying Mechanisms of Right Ventricular Failure in Pulmonary Hypertension
Published on: June 14, 2024
Right ventricle assessment before tricuspid valve interventions
Angelica Cersosimo1, Mara Gavazzoni2, Riccardo Maria Inciardi1
1Department of Medical and Surgical Specialties, Institute of Cardiology, University of Brescia, Brescia.
Guidelines for tricuspid valve interventions focus on annular dilatation, overlooking crucial right ventricular function in severe tricuspid regurgitation. This review explores the prognostic value of right ventricular markers for guiding interventions.
Area of Science:
- Cardiology
- Cardiac Surgery
- Echocardiography
Background:
- Current ESC/EACTS guidelines prioritize tricuspid annular dilatation for intervention in valvular heart disease.
- Comprehensive right ventricular (RV) assessment is vital for patients with severe tricuspid regurgitation (TR) who may benefit from interventions.
- Existing guidelines lack specific thresholds for RV dysfunction, complicating intervention decisions.
Approach:
- This review synthesizes current evidence on the prognostic significance of RV function.
- It examines the role of various RV parameters in patient selection for tricuspid valve interventions.
- The focus is on percutaneous and surgical treatment strategies for severe TR.
Key Points:
- Tricuspid annular dilatation is the primary guideline parameter for intervention, despite RV dysfunction and pulmonary hypertension being critical.
- Accurate assessment of RV function remains challenging, hindering the establishment of intervention thresholds.
- RV function significantly impacts outcomes in patients undergoing tricuspid valve interventions.
Conclusions:
- RV function and dilatation are crucial prognostic indicators in severe tricuspid regurgitation.
- Integrating RV assessment into decision-making can optimize patient selection for tricuspid valve interventions.
- Further research is needed to establish clear thresholds for RV dysfunction in guiding interventions.
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