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Published on: October 16, 2021
Percutaneous Mitral Valve Repair in Pediatric Patients
Firezer Haregu1, Ningyan Wong2, Michael McCulloch3
1Division of Pediatric Cardiology, Department of Pediatrics, University of Virginia Children's Hospital, PO Box 800386, Charlottesville, VA, 22908-0386, USA. fh3d@uvahealth.org.
Insights
Transcatheter Edge-to-Edge Repair is safe and effective for severe secondary mitral regurgitation in adults. This case series reports its use in four pediatric patients, including the youngest and smallest to undergo the procedure.
Area of Science:
- Cardiology
- Interventional Cardiology
- Pediatric Cardiology
Background:
- Transcatheter Edge-to-Edge Repair (TEER) is established for severe secondary mitral regurgitation (MR) in adults.
- Limited data exists for TEER in pediatric populations, with only three prior case reports.
Purpose of the Study:
- To describe the procedural characteristics and outcomes of TEER in pediatric patients.
- To report the use of TEER in the youngest and smallest patients to date.
Main Methods:
- A case series of four pediatric patients undergoing TEER for severe MR.
- Inclusion criteria and procedural details were documented.
Main Results:
- Successful TEER was performed in all four pediatric patients.
- The series includes the youngest and smallest patients reported in the literature.
Conclusions:
- TEER can be safely and effectively applied to pediatric patients with severe MR.
- This case series expands the evidence for TEER in a younger and smaller patient cohort.
Abstract:
Rigorous clinical trials have demonstrated the safety and efficacy of Transcatheter Edge-to-Edge Repair to treat severe secondary mitral regurgitation (MR) in adults with primary cardiomyopathy who have failed guideline-directed medical therapy, as well as those with primary MR at high surgical risk. To date, there are only three case reports describing this procedure in the pediatric population. We report a case series of four pediatric patients, including the youngest and smallest reported, who underwent this procedure.
