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CheXNet and feature pyramid network: a fusion deep learning architecture for multilabel chest X-Ray clinical
Uswatun Hasanah1, Cries Avian1, Jeremie Theddy Darmawan2
1Department of Electronic and Computer Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.
The International Journal of Cardiovascular Imaging
|December 27, 2023
Summary
This study introduces a novel fusion architecture combining CheXNet and Feature Pyramid Network (FPN) for accurate multilabel disease classification in chest X-rays. The new model significantly improves diagnostic speed and performance for thoracic disease detection.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Computer-Aided Diagnosis
Background:
- Multilabel X-ray image analysis is crucial for clinical diagnosis, capturing pathology co-occurrence and interdependency.
- Accurately diagnosing multiple diseases in a single X-ray is challenging due to complex, multi-level features.
- Existing deep learning models aim to enhance classification performance and multi-probability disease detection.
Purpose of the Study:
- To develop an accurate and fast inference system for diagnosing multiple thoracic diseases from chest X-rays.
- To improve the classification and discrimination of multiple diseases in a single X-ray image.
- To enhance clinical diagnosis support systems with advanced AI capabilities.
Main Methods:
- A novel fusion architecture combining CheXNet and Feature Pyramid Network (FPN) was designed.
- The architecture extracts features at different spatial resolutions, capturing both low-level and high-level semantic information.
- The model was evaluated on the NIH ChestXray14 dataset using Area Under the Curve (AUC) and accuracy metrics.
Main Results:
- The proposed method achieved an average AUC of 0.846 and an accuracy of 0.914.
- The architecture demonstrated superior performance compared to other state-of-the-art approaches.
- The model achieved a rapid inference time of 0.013 seconds per image, outperforming existing methods.
Conclusions:
- The fusion architecture shows significant promise for multilabel disease classification in chest X-rays.
- The developed system offers potential applications for quick and accurate clinical diagnosis.
- The study highlights the effectiveness of integrating CheXNet and FPN for enhanced medical image analysis.

