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Related Experiment Video

Updated: Jul 7, 2025

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
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Celiac disease and primary hyperparathyroidism.

Luis Agustín Ramírez Stieben1, Estefanía Pustilnik2, Feldman Néstor Rodolfo3

  • 1Hospital Privado de Rosario. ramirez.stieben@gmail.com.

Revista De La Facultad De Ciencias Medicas (Cordoba, Argentina)
|December 27, 2023
PubMed
Summary
This summary is machine-generated.

This case study details a rare instance of primary hyperparathyroidism and celiac disease coexisting in a patient with osteoporosis. Successful parathyroidectomy improved hormone levels, underscoring the need to investigate secondary causes of bone loss.

Keywords:
celiac diseaseprimary hyperparathyroidismosteoporosis

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Area of Science:

  • Endocrinology
  • Gastroenterology
  • Bone Metabolism

Background:

  • Primary hyperparathyroidism (PHPT) causes hypercalcemia and bone abnormalities.
  • Celiac disease (CD) impairs nutrient absorption, affecting bone health.
  • Both conditions can independently contribute to low bone mass.

Observation:

  • A 49-year-old woman presented with osteoporosis.
  • She was diagnosed with both PHPT and CD.
  • Minimally invasive parathyroidectomy was performed successfully.

Findings:

  • Post-surgery, parathyroid hormone levels decreased.
  • This case demonstrates the rare coexistence of PHPT and CD.
  • The patient's osteoporosis management required addressing both conditions.

Implications:

  • Highlights the importance of investigating secondary causes of osteoporosis.
  • Suggests a potential, though unproven, link between PHPT and CD in bone disease.
  • Further research is warranted to explore shared mechanisms and clinical significance.