Related Experiment Video
Updated: Jul 14, 2026
08:16
One-anastomosis Gastric Bypass (OAGB) in Rats
Published on: November 10, 2018
The intragastric balloon: a novel idea proved ineffective
The British Journal of Surgery
|February 1, 1987
Summary
Intragastric balloons for severe obesity provided minimal, temporary weight loss in a 12-24 month study. Most patients regained weight, showing limited long-term value for obesity treatment.
Area of Science:
- Bariatric Surgery and Interventions
- Gastroenterology
- Obesity Medicine
Background:
- Gross obesity presents significant health challenges requiring effective long-term management strategies.
- Intragastric balloons are a less invasive option for weight management compared to bariatric surgery.
Purpose of the Study:
- To evaluate the long-term efficacy and tolerability of a 600 ml spherical intragastric balloon for treating gross obesity.
Main Methods:
- Twelve severely obese patients (mean weight 121 +/- 22 kg) underwent per-oesophageal insertion of a 600 ml intragastric balloon.
- Patients were monitored for 12-24 months to assess weight changes and balloon tolerability.
Main Results:
- Nine patients initially lost up to 21 kg (mean 11 +/- 6.4 kg) within 3 months, followed by weight regain.
- By 1 year, only one patient maintained weight loss; three patients discontinued the balloon due to intolerance (gastric emptying inhibition).
Conclusions:
- The intragastric balloon demonstrated marginal and temporary weight loss in patients with gross obesity.
- This intervention appears to have no significant long-term value in the comprehensive treatment of severe obesity.
Related Concept Videos
01:16Gastric Emptying
Gastric emptying occurs when the stomach gradually releases chyme into the duodenum. When the stomach is distended, it triggers the release of gastrin, a hormone that promotes gastric acid secretion to aid in digestion. Additionally, stomach distension contributes to peristaltic waves that propel gastric contents toward the pyloric region. The gastroenteric reflex, on the other hand, primarily stimulates peristalsis in the intestines, facilitating the movement of contents further along the...
01:25Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Surgical Interventions for Peptic Ulcer Disease
01:15Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
01:11Pyloric Obstruction
Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...