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Related Concept Videos

Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

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Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
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Dementia01:30

Dementia

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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
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Community Based Intervention01:30

Community Based Intervention

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Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
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Documentation in Long-Term and Home Healthcare Setting01:29

Documentation in Long-Term and Home Healthcare Setting

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Documentation in long-term care facilities and home healthcare settings is crucial for ensuring continuous, coordinated, and comprehensive care for patients. Each setting has its specific documentation processes and tools:
Long-Term Care Facilities
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Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

273
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
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Updated: Jul 7, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

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Multi-Domain Interventions for Dementia Prevention - A Systematic Review.

C B Castro1, L M Costa, C B Dias

  • 1Professor Hamid R. Sohrabi, Centre for Healthy Ageing, Health Futures Institute, Murdoch University, Perth, Australia, Phone: +61 8 9360 6901, E-mail: hamid.sohrabi@murdoch.edu.au; Professor Ralph N. Martins, Centre of Excellence for Alzheimer's Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University, Perth, Australia,

The Journal of Nutrition, Health & Aging
|December 28, 2023
PubMed
Summary
This summary is machine-generated.

Multidomain lifestyle interventions, including diet and exercise, show promise in preventing cognitive decline and dementia in older adults. Two-thirds of studies reviewed indicated cognitive improvements, suggesting these interventions can delay dementia risk.

Keywords:
Lifestyle interventioncognitive trainingdementia preventionnutritionphysical activity

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Area of Science:

  • Gerontology
  • Neuroscience
  • Public Health

Background:

  • The aging global population faces a growing incidence of cognitive decline and dementia.
  • Lifestyle factors like diet, physical activity, and cognitive engagement are potential modulators of cognitive health.
  • Multidomain lifestyle interventions are being explored as a strategy to mitigate dementia risk.

Conclusions:

  • Multidomain lifestyle interventions, particularly those incorporating diet, physical activity, and cognitive training, benefit older adults at risk of dementia.
  • These interventions may prevent or delay cognitive decline in at-risk populations.
  • Future research should focus on longer follow-up periods and study designs to isolate the impact of individual lifestyle components.