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Updated: Jul 7, 2025

Engineered Vascularized Muscle Flap
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[Accurate tissue flap reconstruction method based on the quadratic surface developability for head and neck soft

Chao Chen1,2,3, Yunfeng Liu1,2,3, Jiajie Xu4

  • 1College of Mechanical Engineering, Zhejiang University of Technology, Hangzhou 310023, P. R. China.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi
|December 28, 2023
PubMed
Summary

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Copper-mediated amidation of alkenylzirconocenes with acyl azides: formation of enamides.

Organic letters·2013
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JARID1A, JMY, and PTGER4 polymorphisms are related to ankylosing spondylitis in Chinese Han patients: a case-control study.

PloS one·2013
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[The risk factors of ventilator-associated pneumonia in newborn and the changes of isolated pathogens].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition·2013
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Huan jing ke xue= Huanjing kexue·2013

Digital technology precisely repairs head and neck soft tissue defects after tumor resection. This method enhances surgical accuracy and patient satisfaction, improving aesthetic and functional restoration.

Area of Science:

  • Biomedical Engineering
  • Maxillofacial Surgery
  • Digital Imaging and Simulation

Context:

  • Head and neck tumor resection often results in significant soft tissue defects, impacting patient appearance and psychological well-being.
  • The intricate geometry of the head and neck presents challenges for accurate surgical reconstruction.
  • Current methods struggle to achieve precise aesthetic and functional restoration.

Purpose:

  • To develop and validate a digital precision repair technology for head and neck soft tissue defects.
  • To improve the accuracy and aesthetic outcomes of reconstructive surgery.
  • To enhance patient satisfaction through better functional and cosmetic results.

Summary:

  • A novel digital design method utilizing Gaussian curvature analysis and mechanical constraints was developed to map and reconstruct non-developable head and neck surfaces.
Keywords:
Accurate reconstructionCurved surface developabilityHead and neckSoft tissue defects

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  • An in vitro simulated surgery and clinical verification on a tonsil tumor patient demonstrated the efficacy of this digital approach.
  • The technology facilitates precise flap transplantation and reconstruction for soft tissue defects.
  • Impact:

    • Validates the feasibility of digital precision repair for post-oncologic head and neck reconstruction.
    • Offers surgeons a tool to improve accuracy and aesthetic outcomes in complex reconstructive procedures.
    • Significantly enhances postoperative patient satisfaction by restoring appearance and function.