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Methicillin-resistant Staphylococci in canine pyoderma in Thailand

Putu Ayu Sisyawati Putriningsih1,2, Patchara Phuektes3, Suphattra Jittimanee3

  • 1Graduate School, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.

Veterinary World
|December 28, 2023
PubMed
Abstract

Insights

Methicillin-resistant Staphylococci (MRS) are common in dogs with pyoderma, with over a third of cases showing resistance. Previous antibiotic use is a significant risk factor for this multidrug-resistant infection.

Area of Science:

  • Veterinary Medicine
  • Microbiology
  • Antimicrobial Resistance

Background:

  • Methicillin-resistant Staphylococci (MRS) pose a significant threat to animal and human health.
  • Canine pyoderma, a common skin condition in dogs, is frequently caused by Staphylococci, including MRS.
  • Multidrug-resistant (MDR) strains emerge due to repeated antibiotic use.

Purpose of the Study:

  • To estimate the prevalence of MRS in canine patients.
  • To determine the antibiogram of MRS isolates.
  • To identify risk factors associated with MRS infection in dogs.

Main Methods:

  • Collected skin swabs and clinical data from 56 dogs over one year.
  • Identified Staphylococci species using molecular methods (PCR, sequencing).
  • Assessed antibiotic susceptibility using VITEK® 2 and detected the mecA gene.

Main Results:

  • MRS prevalence was 35.7% (20/56 dogs).
  • Methicillin-resistant Staphylococcus pseudintermedius was prevalent (23.1% of isolates), and all were MDR.
  • Recent systemic antibiotic use was a significant risk factor for MRS infection (p < 0.05).

Conclusions:

  • High prevalence of MRS and MDR strains observed in canine patients.
  • Improper antibiotic use and gene transfer may contribute to the spread of resistance.
  • Effective preventive strategies are crucial for controlling MRS in canine populations.
Keywords:
StaphylococciThailandantibiogrammethicillin-resistantprevalencerisk factor

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