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Methicillin-resistant Staphylococci in canine pyoderma in Thailand
Putu Ayu Sisyawati Putriningsih1,2, Patchara Phuektes3, Suphattra Jittimanee3
1Graduate School, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Veterinary World
|December 28, 2023
Summary
Methicillin-resistant Staphylococci (MRS) are common in dogs with pyoderma, with over a third of cases showing resistance. Previous antibiotic use is a significant risk factor for this multidrug-resistant infection.
Area of Science:
- Veterinary Medicine
- Microbiology
- Antimicrobial Resistance
Background:
- Methicillin-resistant Staphylococci (MRS) pose a significant threat to animal and human health.
- Canine pyoderma, a common skin condition in dogs, is frequently caused by Staphylococci, including MRS.
- Multidrug-resistant (MDR) strains emerge due to repeated antibiotic use.
Purpose of the Study:
- To estimate the prevalence of MRS in canine patients.
- To determine the antibiogram of MRS isolates.
- To identify risk factors associated with MRS infection in dogs.
Main Methods:
- Collected skin swabs and clinical data from 56 dogs over one year.
- Identified Staphylococci species using molecular methods (PCR, sequencing).
- Assessed antibiotic susceptibility using VITEK® 2 and detected the mecA gene.
Main Results:
- MRS prevalence was 35.7% (20/56 dogs).
- Methicillin-resistant Staphylococcus pseudintermedius was prevalent (23.1% of isolates), and all were MDR.
- Recent systemic antibiotic use was a significant risk factor for MRS infection (p < 0.05).
Conclusions:
- High prevalence of MRS and MDR strains observed in canine patients.
- Improper antibiotic use and gene transfer may contribute to the spread of resistance.
- Effective preventive strategies are crucial for controlling MRS in canine populations.
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