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Updated: Jul 6, 2025

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
An Observational Study on Cystic Alterations in Normal Dental Follicles Associated with Impacted Lower Third Molar
Sruthi T Sundaran1, Roshni Abida2, Sachin A Aslam2
1Department of Oral and Maxillofacial Surgery, MES Dental College, Kerala, India, Phone: +91 8086960285,
Aim:
To evaluate the cystic changes in the radiographically normal dental follicle associated with impacted mandibular third molar.
Materials And Methods:
This study was conducted on 80 patients. Samples were selected using a convenient sampling technique from the patients who had impacted mandibular third molars in Pell and Gregory's positions B and C, with follicular space less than 2.5 mm in diameter. After surgical removal of an impacted tooth, the dental follicle was sent for histopathologic evaluation.
Results:
Pathologic alterations were found in 19% of cases out of 80 samples. Odontogenic keratocystic and dentigerous cystic changes were found in 7% of cases. A statistically significant cystic alteration was found in female patients and distoangular impacted teeth.
Conclusion:
This study shows a significant cystic alteration in the radiologically normal dental follicles. Clinical and radiographic features alone may not be a reliable indicator of the absence of pathology. Early intervention of impacted teeth will help to reduce morbidity due to the development of pathology.
Clinical Significance:
This study will help educate patients on the risks of retaining impacted teeth, based on scientific facts, in order to minimize the risks and to assess the correlation of pathologic alterations with the depth of impaction and angular position of the impacted tooth.
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