Clinical considerations on the metastases of mammarian cancer

The Authors examine the prognostic value of metastatic breast cancer and the consequent possibility of therapy. They discuss the role of steroid receptor determination both in prognosis and in planning treatment. Their personal experience confirms the positivity of Progestinic receptors as a more specific index of hormono-sensitivity in regard to the positivity of the single estrogen receptors. Concerning therapy, in metastatic breast cancer the association between chemo- and hormono-therapy may offer better results, acting on different cell populations, though it probably does not improve the survival rate.