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Effect of constipation on readmission for heart failure in patients with acute heart failure

Shigeto Namiuchi1, Atsushi Tanita1, Shinichiro Sunamura1

  • 1Department of Cardiology, Sendai City Medical Center, Sendai, Japan.

ESC Heart Failure
|December 30, 2023
PubMed

Insights

Constipation significantly increases heart failure readmission risk in acute patients. This study highlights the importance of managing constipation for better heart failure prognosis and reducing hospital readmissions.

Area of Science:

  • Cardiology
  • Gastroenterology
  • Clinical Research

Background:

  • Constipation is a prevalent gastrointestinal issue linked to cardiovascular events.
  • While common in heart failure patients, its prognostic impact remains understudied.
  • Acute heart failure (AHF) management often overlooks constipation's role.

Purpose of the Study:

  • To investigate the association between constipation and prognosis in patients with acute heart failure.
  • To determine if constipation impacts heart failure readmission rates and overall mortality.

Main Methods:

  • A cohort of 397 acute heart failure patients (mean age 81 years) was analyzed.
  • Constipation was defined by regular laxative use or ICD diagnosis.
  • Kaplan-Meier and Cox proportional hazards analyses were performed post-propensity score matching.

Main Results:

  • Constipation was significantly associated with a higher risk of heart failure readmission (log-rank P=0.0027).
  • Adjusted analyses showed a 2.61-fold increased hazard ratio for readmission in constipated patients (P=0.0032).
  • No significant difference in all-cause mortality risk was observed between groups.

Conclusions:

  • Constipation is a significant independent predictor of heart failure readmission.
  • Managing constipation may improve outcomes for acute heart failure patients.
  • Further research should explore interventions for constipation in heart failure care.
Abstract

Keywords:
ConstipationHeart failurePrognosisRehospitalization

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