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Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
Published on: July 16, 2017
Tools for assembling the cell: Towards the era of cell structural bioinformatics
Mengzhou Hu1, Xikun Zhang, Andrew Latham
1Department of Medicine, University of California San Diego, San Diego, CA, USA†These authors contributed equally.
None:
Cells consist of large components, such as organelles, that recursively factor into smaller systems, such as condensates and protein complexes, forming a dynamic multi-scale structure of the cell. Recent technological innovations have paved the way for systematic interrogation of subcellular structures, yielding unprecedented insights into their roles and interactions. In this workshop, we discuss progress, challenges, and collaboration to marshal various computational approaches toward assembling an integrated structural map of the human cell.
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