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Updated: Jul 6, 2025

An Injury Paradigm to Investigate Central Nervous System Repair in Drosophila
Published on: March 28, 2013
Molecular aspects of regeneration in insects
Shivali Pandita1, Sanchita Singh2, Sanjay Kumar Bajpai3
1CSIR-National Botanical Research Institute, (Council of Scientific and Industrial Research) Rana Pratap Marg, Lucknow, UP, 226001, India; Department of Zoology, University of Lucknow, Lucknow, Uttar Pradesh, 226007, India.
Abstract:
Regeneration is a fascinating phenomenon observed in various organisms across the animal kingdom. Different orders of class Insecta are reported to possess comprehensive regeneration abilities. Several signalling molecules, such as morphogens, growth factors, and others trigger a cascade of events that promote wound healing, blastema formation, growth, and repatterning. Furthermore, epigenetic regulation has emerged as a critical player in regulating the process of regeneration. This report highlights the major breakthrough research on wound healing and tissue regeneration. Exploring and reviewing the molecular basis of regeneration can be helpful in the area of regenerative medicine advancements. The understanding gathered from this framework can potentially contribute to hypothesis designing with implications in the field of synthetic biology and human health.
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