Related Experiment Video
Updated: Jul 6, 2025
10:46
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
10.7K
Sleep disorders in patients with multiple sclerosis in Spain
G X Zhang1, W T Zhang2, S S Gao2
1Multiple Sclerosis Unit, Neurology Service, Vithas Nisa Hospital, Seville, Spain; Department of Neurology, Yan'an University Medical College No. 3 Affiliated Hospital, Shaanxi, China; International Doctoral School, University of Seville, Spain.
Neurologia
|December 31, 2023
Summary
Sleep disturbances are highly prevalent in multiple sclerosis (MS) patients, affecting three out of four individuals. Both increasing age and greater disability are linked to a higher frequency and severity of these sleep issues in MS.
Area of Science:
- Neurology
- Sleep Medicine
- Clinical Research
Background:
- Sleep disturbances are a common but often overlooked issue in patients with multiple sclerosis (MS).
- Understanding the factors contributing to sleep problems in MS is crucial for improving patient quality of life.
Purpose of the Study:
- To assess the prevalence of sleep disturbances in patients with MS.
- To investigate the relationship between sleep disturbances and clinical (e.g., disability, MS form) and demographic (e.g., age) variables in MS patients.
Main Methods:
- The Pittsburgh Sleep Quality Index (PSQI) was administered to 221 patients with MS.
- Usable data from 142 patients were collected and analyzed to identify sleep disorders and associated factors.
Main Results:
- A high prevalence of sleep disturbances was found in 74.7% of MS patients, exceeding rates in the general population.
- Sleep disorder frequency and severity increased with age and the degree of disability (Expanded Disability Status Scale scores).
- Patients with secondary progressive MS reported more sleep disturbances than those with primary progressive MS.
Conclusions:
- Sleep disorders are significantly more common in patients with MS compared to other populations.
- Age and disability severity are positively correlated with the prevalence and severity of sleep disturbances in MS.
- Targeted interventions for sleep disturbances may be beneficial for MS patients, particularly those with progressive forms, advanced age, or higher disability.
Related Concept Videos
01:15REM Sleep Behavior Disorder
195
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...
195
01:19Management of Insomnia
253
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
253
01:24Substance Use Disorders Affecting Sleep
169
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
169
01:07Narcolepsy
103
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
103
01:24Sleep-Wake Cycles
1.3K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.3K
01:27Restless Leg Syndrome and Night Terrors
180
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
180