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Triphenyl phosphate allergy from spectacle frames.

L Carlsen, K E Andersen, H Egsgaard

    Contact Dermatitis
    |November 1, 1986
    PubMed
    Summary
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    Triphenyl phosphate allergy can occur from spectacle frames. Patch testing identified triphenyl phosphate and tri-m-cresyl phosphate as allergens in this case.

    Area of Science:

    • Allergy and Immunology
    • Dermatology
    • Ophthalmology

    Background:

    • Allergic contact dermatitis is a common skin condition.
    • Spectacle frames can contain various chemicals that may cause allergic reactions.
    • Identifying specific allergens is crucial for effective management.

    Observation:

    • A patient presented with suspected allergy to spectacle frames.
    • Patch testing was performed using triphenyl phosphate (TPP), tri-m-cresyl phosphate (TMCP), and tri-p-cresyl phosphate (TPCP) at varying concentrations.
    • Gas chromatography revealed TPP contamination in the TMCP patch test material.

    Findings:

    • The patient showed positive patch test reactions to 0.05% TPP and 0.5% TMCP.
    • No reaction was observed with TPCP.

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  • The detected TPP concentration (0.08%) in the patch test material exceeded the patient's allergy threshold.

    • Implications:

    • This case highlights TPP as a potential allergen in spectacle frame-related contact dermatitis.
    • Accurate allergen identification requires careful consideration of contaminants in testing materials.
    • Awareness of TPP allergy can aid in diagnosing and managing similar cases, improving patient comfort and adherence to eyewear.