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Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding

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G protein-coupled receptors and obesity

Alessandro Pocai1

  • 1Cardiovascular and Metabolic Disease, Johnson & Johnson Innovative Medicine Research & Development, Spring House, PA, United States.

Frontiers in Endocrinology
|January 1, 2024
PubMed
Summary

New anti-obesity medications targeting G protein-coupled receptors (GPCRs) offer significant weight loss and cardiovascular benefits. The development of therapies like glucagon like peptide 1 receptor agonists (GLP-1RAs) is transforming obesity management.

Keywords:
GIPGLP-1amylinglucagonobesitysemaglutidetirzepatide

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