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Updated: Jul 6, 2025

Author Spotlight: Gastric Epithelial Cell Responses in Helicobacter pylori infection
Published on: July 5, 2024
Helicobacter pylori-Induced Gastroduodenal Stricture in a Child
Sofia Zeidan1, Albert Jeh Seng Chang2, Trinh Thi Nhat Truong3
1Davis School of Medicine, University of California, Sacramento, CA.
Abstract:
Helicobacter pylori is a known cause of peptic ulcers, but it has not been reported to cause strictures in children. We present the case of a previously healthy 12-year-old boy with sudden onset of abdominal pain and vomiting, positive stool H. pylori antigen testing, and esophagogastroduodenoscopy revealing a gastroduodenal stricture causing gastric outlet obstruction. Because of medically refractory disease, he ultimately required laparoscopic truncal vagotomy with open pyloroplasty. This is an unusually severe presentation and may warrant H. pylori being on the differential of pediatric gastrointestinal strictures as well as further discussion on other long-term implications.
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