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[Association Between Different Modes of Respiratory Support and Feeding Intolerance in Preterm Infants: A

Ting Zhang1,2, Yi Feng1,2, Yong Hu1,2

  • 1（ 610041） Neonatal Intensive Care Unit, West China Second University Hospital, Sichuan University, Chengdu 610041, China.

Sichuan Da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition
|January 1, 2024
PubMed

Insights

High flow nasal cannula (HFNC) may reduce feeding intolerance in preterm infants. Other respiratory support modes like nasal continuous positive airway pressure (NCPAP), bilevel positive airway pressure (BIPAP), and invasive ventilation may increase feeding intolerance risk.

Area of Science:

  • Neonatal Medicine
  • Pediatric Gastroenterology
  • Respiratory Care

Context:

  • Preterm infants often require respiratory support, increasing their risk of feeding intolerance.
  • Enteral feeding is crucial for preterm infant growth but can be complicated by respiratory support needs.

Purpose:

  • To investigate the association between various respiratory support methods and feeding intolerance in hospitalized preterm infants.
  • To offer evidence-based recommendations for optimizing enteral feeding strategies in this vulnerable population.

Summary:

  • A retrospective study analyzed 272 preterm infants, comparing feeding intolerance incidence across different respiratory support modes.
  • High flow nasal cannula (HFNC) showed a trend towards reduced feeding intolerance compared to normobaric oxygen.
  • Nasal continuous positive airway pressure (NCPAP), bilevel positive airway pressure (BIPAP), and invasive ventilation were associated with a potential increase in feeding intolerance, though statistical significance was not reached.

Impact:

  • Findings suggest HFNC may be a preferred respiratory support method to minimize feeding intolerance in preterm infants.
  • Highlights the need for careful enteral feeding management when utilizing NCPAP, BIPAP, or invasive ventilation.
  • Underscores the necessity for larger studies to confirm these associations and refine clinical guidelines.
Abstract

Keywords:
Enteral feedingFeeding intolerancePreterm infantsRespiratory supportRetrospective cohort study

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