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Coronavirus Disease 2019-induced Acute Exudative Polymorphous Vitelliform Maculopathy
Mohamed Osman1, Omar Mehana1, Mahmoud Eissa2
1Department of Ophthalmology, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Middle East African Journal of Ophthalmology
|January 1, 2024
Summary
Acute exudative polymorphous vitelliform maculopathy (AEPVM) can occur after COVID-19 infection. This rare condition involves macular detachment and vitelliform deposits, which may resolve spontaneously.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Acute exudative polymorphous vitelliform maculopathy (AEPVM) is a rare condition.
- It is characterized by macular detachment and vitelliform deposits.
- AEPVM is often linked to retinal pigment epithelial dysfunction and malignancies.
Observation:
- A 32-year-old woman presented with acute bilateral visual disturbance post-COVID-19 diagnosis.
- Fundus examination revealed bilateral multifocal subretinal deposits.
- Spectral-domain optical coherence tomography confirmed serous retinal detachment with vitelliform deposits.
Findings:
- The patient's condition was not associated with malignancy or genetic disorders.
- No specific treatment was administered.
- Vitelliform deposits gradually resolved over 18 months.
Implications:
- COVID-19 infection may be a potential trigger for AEPVM.
- This case highlights a possible association between AEPVM and viral infections.
- Further research is needed to understand the link between COVID-19 and retinal disorders.

