Homeostasis and information processing: The key frames for the thermodynamics of biological systems

Life is a natural phenomenon ineluctably subject to the laws and principles of physics. In this framework, thermodynamics has a crucial role, since living beings are structured on a molecular and cellular basis that can only be maintained with extensive energy consumption. This imposes that living beings are necessarily open systems. But the survival of each type of organism depends on the relative stability of certain essential variables, even in the presence of the disturbances to which they are subjected. The stability of these variables is relative in the sense that they have a narrow range of variation. This stability of the essential variables is a consequence of refined control mechanisms developed in the course of evolution, that lead to the condition called homeostasis. This homeostasis requires that control mechanisms process the various types of information related to the internal structure of the organism and its environment. Consequently, a biological system, through information processing aimed at guiding the mechanisms that maintain its homeostasis, manages the conditions imposed by the principles of thermodynamics, obtaining the most efficient use of energy possible and keeping entropic degradation controlled. In this article, we discuss the close links between thermodynamics, homeostasis and the information processing necessary to maintain homeostasis.