Related Experiment Video
Updated: Jul 6, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Cardiovascular Risk Scoring of Hospitalized Chronic Kidney Disease Patients by Framingham Risk Score
1Dr Mohammad Khurshadul Alam, Medical Officer, National Institute of Cardiovascular Disease (NICVD), Dhaka, Bangladesh;
Chronic kidney disease (CKD) patients face high cardiovascular disease (CVD) risks. This study found age, male gender, smoking, and high cholesterol are key CVD risk factors in CKD patients.
Area of Science:
- Nephrology
- Cardiology
- Public Health
Background:
- Patients with chronic kidney disease (CKD) exhibit a significantly higher prevalence of cardiovascular diseases (CVD).
- Assessing cardiovascular risk is crucial for managing CKD patients and preventing adverse events.
Purpose of the Study:
- To estimate the risk of cardiovascular events in chronic kidney disease patients using Framingham's Risk Score.
- To identify predominant cardiovascular risk factors among CKD patients.
Main Methods:
- A cross-sectional descriptive study involving 100 CKD patients admitted to Chittagong Medical College Hospital.
- Cardiovascular risk was assessed using Framingham's criteria, with estimated glomerular filtration rate (eGFR) calculated via the MDRD formula.
- Data were analyzed using SPSS-18.0.
Main Results:
- Most patients were under 60 years old, with males (56.0%) more prevalent than females (44.0%).
- Males were predominantly in the high-risk cardiovascular group. Higher risk was associated with elevated total cholesterol (212.17mg/dl) and low HDL (38.58mg/dl).
- Significant positive correlations were observed between age and serum total cholesterol with cardiovascular risk scoring.
Conclusions:
- Age, male gender, smoking, and high total cholesterol are significant cardiovascular risk factors in CKD patients.
- The findings highlight the need for targeted cardiovascular risk management strategies in CKD populations.
More Related Videos
Related Concept Videos
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
Renal Failure: Dose Adjustments
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Heart Failure Drugs: Diuretics
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...

