Malakoplakia of the small intestine presenting as an abdominal mass

Area of Science:

• Pathology
• Gastroenterology
• Immunology

Background:

• Malakoplakia is a rare chronic granulomatous disease.
• It typically affects the urinary and gastrointestinal tracts.
• Immunocompromised individuals are predominantly affected.

Observation:

• This case report details a rare instance of malakoplakia.
• The presentation involved an abdominal mass with extensive intestinal and pelvic disease.
• A superficial polymicrobial abscess complicated the condition.

Findings:

• Histologic examination revealed characteristic features such as von Hansemann cells and Michaelis-Gutmann bodies.
• Clinical manifestations varied, including cutaneous lesions, urinary symptoms, and hematochezia.
• The case underscores the diverse clinical spectrum of malakoplakia.

Implications:

• Understanding the proposed pathogenesis is crucial for diagnosis.
• Recognizing the variable clinical presentations aids in early detection.
• Effective surgical management is key for patients with extensive malakoplakia.